May Lisinopril help us?

uses of Lisinopril

Lisinopril belongs to a group of medications called ACE inhibitors. It's used to treat high blood pressure ( hypertension ) in adults and in children 6 years of age and older. It works by relaxing blood vessels, causing them to widen. High blood pressure reduction helps prevent strokes, heart attacks and kidney problems.

Lisinopril is also used after an acute heart attack to improve survival, and is used with other drugs ( e. g. , " water pills " /diuretics, digoxin ) to treat congestive heart failure.

how to use of Lisinopril

Take Lisinopril by mouth, usually once a day or as directed by your doctor. We may take Lisinopril with or without food. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at same time each day.

If we are taking Lisinopril in liquid suspension form, shake bottle well before each use. Measure dose out carefully.

Do not take potassium supplements or salt substitutes containing potassium without talking to your doctor or pharmacist first. This medicine can raise your potassium levels, which rarely can cause serious side effects such as muscle weakness or very slow heartbeats. Tell your doctor immediately if these effects occur.

The dosage is based on your medical condition and response to therapy. For the treatment of high blood pressure, it may take 2 to 4 weeks before full benefit of Lisinopril occurs. It may take several weeks or months to see full benefit when Lisinopril is used for congestive heart failure.

It's important to continue taking Lisinopril even if we feel well. Most people with high blood pressure do not feel sick.

other used of Lisinopril

This section contains uses of Lisinopril that aren't listed in approved professional labeling for drug but that may be prescribed by your health care professional. Use Lisinopril for a condition that's listed in this section only if it has been so prescribed by your health care professional.

Lisinopril may also be used to help protect kidneys from damage due to diabetes.

side effects of Lisinopril

We may experience headache, dizziness, lightheadedness, fatigue, nausea, diarrhea, dry cough or blurred vision as your body adjusts to medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed Lisinopril because he or she has judged that benefit to you is greater than the risk of side effects. Many people using Lisinopril do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

Tell your doctor immediately if any of these highly unlikely but very serious side effects occur:

Lisinopril may rarely cause serious ( possibly fatal ) liver problems. If we notice any of following highly unlikely but very serious side effects, seek immediate medical attention:

A very serious allergic reaction to Lisinopril is rare. However, seek immediate medical attention if we notice any symptoms of a serious allergic reaction, including:

This isn't a complete list of possible side effects. If we notice other effects not listed above, contact your doctor or pharmacist.

precautions of Lisinopril

Before taking Lisinopril, tell your doctor or pharmacist if you're allergic to it; or to other ACE inhibitors ( e. g. , captopril, benazepril ) ; or if we have any other allergies ( including an allergic reaction after exposure to certain membranes used for blood filtering ) .

Lisinopril shouldn't be used if we have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if we have:

Before using Lisinopril, tell your doctor or pharmacist your medical history, especially of:

Lisinopril may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages.

To minimize dizziness and lightheadedness due to lowering of your blood pressure, get up slowly when rising from a seated or lying position. Serious loss of body water can also lower your blood pressure and worsen dizziness. Drink adequate fluids to prevent from becoming dehydrated. If we are on restricted fluid intake, consult your doctor for further instructions. Be careful not to become too overheated during exercise which can lead to excessive sweating. Consult your doctor if we experience severe vomiting or diarrhea.

Before having surgery, tell your doctor or dentist that you're taking Lisinopril.

Caution is advised when using Lisinopril in elderly because they may be more sensitive to the effects of drug, especially dizziness effect.

Lisinopril isn't recommended for use during pregnancy due to the risk for harm to an unborn baby. Consult your doctor for more details. ( See also Warning section. )

It's not known if Lisinopril passes into breast milk. Breast-feeding is not recommended due to potential harm to nursing infant. Consult your doctor before breast-feeding.

interactions of Lisinopril

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring we for them. Don't start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using Lisinopril, tell your doctor or pharmacist of all prescription and nonprescription products we may use, especially of:

A very serious reaction may occur while use Lisinopril if we are getting injections for bee/wasp sting allergy ( desensitization ) and are also taking Lisinopril. Make sure all your doctors know which medicines we are using.

Check labels on all your medicines ( e. g. , cough-and-cold products, diet aids ) because they may contain ingredients that could increase your heart rate or blood pressure. Ask your pharmacist about safe use of those products.

This document doesn't contain all possible interactions. Therefore, before using Lisinopril, tell your doctor or pharmacist of all products we use. Keep a list of all your medications with you, and share list with your doctor and pharmacist.

Lisinopril with US shipping

Cholesterol, Blood Pressure Control May Reverse Atherosclerosis In Adults With Diabetes

Aggressively lowering cholesterol and blood pressure levels below current targets in adults with type 2 diabetes may help to prevent - and possibly reverse - hardening of arteries, according to new research supported by National Heart, Lung, and Blood Institute ( NHLBI ) of the National Institutes of Health. Hardening of arteries, also known as atherosclerosis, is number one cause of heart disease and can lead to heart attack, stroke, and death.

The three-year study of 499 participants is first to compare two treatment targets for LDL ( 'bad' ) cholesterol and systolic blood pressure levels, key risk factors for heart disease, in people with diabetes. Results are published in April 9 issue of Journal of American Medical Association.

" This study provides good news for adults with type 2 diabetes, " said Elizabeth G. Nabel, M. D. , NHLBI director. " These patients are two to four times more likely than people without diabetes to die from heart disease. For first time, we've evidence that aggressively lowering LDL cholesterol and blood pressure can actually reverse damage to arteries in middle-aged adults with diabetes. "

In Stop Atherosclerosis in Native Diabetics Study ( SANDS ) , approximately one-half of participants ( 247 ) were asked to lower to standard levels their LDL cholesterol ( to 100 milligrams per deciliter ) and blood pressure ( systolic blood pressure of 130 mmHg or lower ) , while the other half ( 252 ) aimed for more aggressive lowering of LDL cholesterol to 70 mg/dL or lower and of systolic blood pressure to 115 mmHg or lower. All participants were American Indians 40 years or older ( average age of 56 ) who had diabetes, high blood cholesterol, and high blood pressure but no history of heart attack or other evidence of heart disease. The study was conducted at four clinical centers in southwestern Oklahoma; Phoenix, Ariz. ; northeastern Arizona; and South Dakota. All participants continued to receive their medical care, including diabetes management, dietary and exercise counseling, and smoking cessation, from their health care providers with Indian Health Service. Like NIH, Indian Health Service is part of U. S. Department of Health and Human Services.

" American Indians have a high rate of diabetes and cardiovascular disease related to diabetes, but there are few clinical trials that address these issues in this population, " said Barbara V. Howard, Ph. D. , of MedStar Research Institute in Hyattsville, Md. , lead author of paper. " These study results provide needed evidence to help develop community-based programs to treat and prevent epidemic of cardiovascular disease among American Indians. At the same time, we're increasing our understanding of effects of intensively lowering cholesterol and blood pressure in adults with type 2 diabetes, which might also apply to other populations. "

During three-year study, participants were examined by study clinicians one month after enrollment, then every three months, to assess their blood cholesterol and blood pressure levels and general well being. Food and Drug Administration-approved blood pressure and cholesterol medications were added and adjusted as needed to help participants achieve their treatment goals. The same medications were available to participants in standard and the aggressive treatment groups. Participants were also encouraged to follow lifestyle approaches to help meet their blood pressure and cholesterol treatment targets, such as following a heart-healthy eating plan, being physically active, maintaining a healthy weight, and not smoking.

To assess impact of treatments on the participants' cardiovascular health, researchers used ultrasound to measure thickness of the carotid ( neck ) artery -- an indication of hardening of arteries, a leading effect of high blood pressure and cholesterol and an early sign of cardiovascular disease. In addition, ultrasound was also used to measure the size and function of left ventricle, the heart's main pumping chamber. Enlarged hearts are known to be predictors of increased risk of heart attack and stroke. These measurements were taken at enrollment, at 18 months, and at 36 months, when the study ended.

On average, participants in both groups reached and maintained their target goals for blood cholesterol and blood pressure levels. The numbers of heart attacks and other cardiovascular events were similar between two groups and lower than expected.

In addition, carotid artery thickness measurements of participants in aggressive treatment group were significantly lower than those in standard treatment group. Researchers report that, compared to baseline, carotid artery thickness increased slightly in the standard group and regressed in aggressive treatment group, indicating a partial reversal of atherosclerosis. Furthermore, although heart size decreased from baseline in both groups, beneficial change was significantly greater among participants in aggressive treatment group.

" Many patients with diabetes don't reach their blood pressure and cholesterol goal levels and thus remain at high risk for heart attacks and stroke, " noted Howard. " In our study, participants successfully managed their blood cholesterol and blood pressure to reach their goal levels. Our message to doctors, nurses, and patients is that you can reach your goal levels, and we should work together to help you do that. "

As with any therapy, benefits and risks must be considered for each patient. In SANDS, participants in aggressive treatment group on average needed more medications and higher doses than standard treatment group, and they were slightly more likely to have side effects from blood pressure-lowering medications than those in standard group. Such adverse effects generally resolved, however, after the medication was changed or dose reduced. There were no differences in side effects related to cholesterol-lowering drugs between standard and aggressive treatment groups.

" These encouraging findings from SANDS suggest that more aggressive blood pressure and cholesterol targets than those currently recommended in patients with diabetes may reduce their future cardiovascular risk, " said Jerome L. Fleg, M. D. , NHLBI project officer of the study and a coauthor of paper. " Longer term followup of this population as well as additional studies in other populations are needed to confirm the benefit and cost-effectiveness of these lower targets. "

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Medications used in this study were donated by First Horizon Pharmacy, Merck and Co. , and Pfizer, Inc.

An estimated 21 million Americans have diabetes and 284, 000 die from it each year. Sixty-five percent of the deaths are related to cardiovascular causes.

Part of the National Institutes of Health, National Heart, Lung, and Blood Institute ( NHLBI ) plans, conducts, and supports research related to causes, prevention, diagnosis, and treatment of heart, blood vessel, lung, and blood diseases; and sleep disorders. The Institute also administers national health education campaigns on women and heart disease, healthy weight for children, and other topics. NHLBI press releases and other materials are available online at www. nhlbi. nih. gov.

The National Institutes of Health ( NIH ) - The Nation's Medical Research Agency - includes 27 Institutes and Centers and is a component of U. S. Department of Health and Human Services. It's primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http: //www. nih. gov.

Resources:

* Your Guide to Living Well With Heart Disease, http: //www. nhlbi. nih. gov/health/public/heart/other/your_guide/living_well. htm

* Atherosclerosis, http: //www. nhlbi. nih. gov/health/dci/Diseases/Atherosclerosis/Atherosclerosis_WhatIs. html

* National Diabetes Information Clearinghouse, http: //diabetes. niddk. nih. gov/

* National Diabetes Education Program http: //ndep. nih. gov/

Source: NHLBI Communications Office NIH/National Heart, Lung and Blood Institute

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